BDBM50007070 2-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-benzoic acid methyl ester::CHEMBL76929::methyl 2-hydroxy-4-(4-(2-nitrovinyl)phenoxysulfonyl)benzoate

SMILES COC(=O)c1ccc(cc1O)[S+]([O-])(=O)Oc1ccc(\C=C\[N+]([O-])=O)cc1

InChI Key InChIKey=CMWPATODJXDHES-CMDGGOBGSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007070   

TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
TBA

Curated by ChEMBL
LigandPNGBDBM50007070(2-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Abelson murine leukemia virus p60 v-ablMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50007070(2-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-be...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50007070(2-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-be...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of the epidermal growth factor receptor expressed in A431 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50007070(2-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-be...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed