BDBM50007130 1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol::CHEMBL86576

SMILES NC[C@@H]1OC(COc2ccccc2)Cc2c(O)c(O)ccc12

InChI Key InChIKey=KOHDNXKBNHHXKQ-INSVYWFGSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50007130   

TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007130(1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol ...)
Affinity DataKi:  374nMAssay Description:Binding affinity using [3H]-spiperone radioligand competitive binding assay against dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007130(1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol ...)
Affinity DataKi:  1.28E+3nMAssay Description:Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007130(1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol ...)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007130(1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol ...)
Affinity DataEC50:  40nMAssay Description:Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007130(1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol ...)
Affinity DataEC50:  24nMAssay Description:Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed