BDBM50007146 1-Aminomethyl-3-hexyl-isochroman-5,6-diol::CHEMBL420972

SMILES CCCCCCC1Cc2c(O)c(O)ccc2[C@H](CN)O1

InChI Key InChIKey=HMYHFTUKXYGDQG-MHTVFEQDSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50007146   

TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007146(1-Aminomethyl-3-hexyl-isochroman-5,6-diol | CHEMBL...)
Affinity DataKi:  704nMAssay Description:Binding affinity using [125 I] SCH 23982 radioligand competitive binding assay on dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007146(1-Aminomethyl-3-hexyl-isochroman-5,6-diol | CHEMBL...)
Affinity DataKi:  5.54E+3nMAssay Description:Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007146(1-Aminomethyl-3-hexyl-isochroman-5,6-diol | CHEMBL...)
Affinity DataEC50:  14nMAssay Description:Concentration required to inhibit 50% dopamine receptor D1 activity using cell free homogenate of carp retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007146(1-Aminomethyl-3-hexyl-isochroman-5,6-diol | CHEMBL...)
Affinity DataEC50:  782nMAssay Description:Concentration required to inhibit 50% dopamine receptor D2 in a cell free homogenate of intermediate lobe of pituitary glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50007146(1-Aminomethyl-3-hexyl-isochroman-5,6-diol | CHEMBL...)
Affinity DataEC50:  23nMAssay Description:Inhibition of Dopamine receptor D1 activity by functional cyclase assay using cell free homogenate of rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed