BDBM50007158 (S)-2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone(BRL 52537)::2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-piperidin-1-yl)-ethanone::CHEMBL71294

SMILES Clc1ccc(CC(=O)N2CCCC[C@H]2CN2CCCC2)cc1Cl

InChI Key InChIKey=GHCCBWMZKJQGLS-HNNXBMFYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50007158   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Zambeletti Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007158((S)-2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylme...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Zambeletti Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007158((S)-2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylme...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pigMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Zambeletti Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007158((S)-2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylme...)
Affinity DataKi:  1.00E+3nMAssay Description:Affinity for opioid receptor delta sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Zambeletti Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007158((S)-2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylme...)
Affinity DataKi:  1.56E+3nMAssay Description:Affinity for opioid receptor mu sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Zambeletti Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50007158((S)-2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylme...)
Affinity DataKi:  1.56E+3nMAssay Description:Displacement of [3H]-DAGO from mu opioid receptors in guinea pig brain (minus cerebellum).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed