BDBM50007234 7-Fluoro-1,3-dihydro-imidazo[4,5-b]quinolin-2-one::CHEMBL323071

SMILES Fc1ccc2nc3[nH]c(=O)[nH]c3cc2c1

InChI Key InChIKey=XTXHKKBSLRGOJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007234   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007234(7-Fluoro-1,3-dihydro-imidazo[4,5-b]quinolin-2-one ...)
Affinity DataIC50:  300nMAssay Description:Inhibition of hydrolysis of c-AMP phosphodiesterase in human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50007234(7-Fluoro-1,3-dihydro-imidazo[4,5-b]quinolin-2-one ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of cGMP hydrolysis by human platelet phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed