BDBM50007261 CHEMBL102091::Sodium; 7-[4-(4-fluoro-phenyl)-2-isopropyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoate

SMILES CC(C)c1c(CCC(O)C[C@@H](O)CC([O-])=O)c(cn1-c1ccccc1)-c1ccc(F)cc1

InChI Key InChIKey=UBFHWBHHCSSZAB-FOIFJWKZSA-M

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007261   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007261(CHEMBL102091 | Sodium; 7-[4-(4-fluoro-phenyl)-2-is...)
Affinity DataIC50: <0.0100nMAssay Description:In vitro inhibition of HMG-CoA reductase of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007261(CHEMBL102091 | Sodium; 7-[4-(4-fluoro-phenyl)-2-is...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of solubilized HMG-CoA reductase in rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007261(CHEMBL102091 | Sodium; 7-[4-(4-fluoro-phenyl)-2-is...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of HMG-CoA reductase of rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed