BDBM50007265 CHEMBL102112::Sodium; 3,5-dihydroxy-6-(2-methyl-4-phenyl-quinolin-3-yloxy)-hexanoate

SMILES Cc1nc2ccccc2c(-c2ccccc2)c1OCC(O)C[C@@H](O)CC([O-])=O

InChI Key InChIKey=IAIQZRIQFGXCEB-TZHYSIJRSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007265   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007265(CHEMBL102112 | Sodium; 3,5-dihydroxy-6-(2-methyl-4...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007265(CHEMBL102112 | Sodium; 3,5-dihydroxy-6-(2-methyl-4...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed