BDBM50007267 CHEMBL321768::Sodium; 6-(4'-fluoro-5-hydroxy-3,4,6-triisopropyl-biphenyl-2-yloxy)-3,5-dihydroxy-hexanoate

SMILES CC(C)c1c(O)c(C(C)C)c(-c2ccc(F)cc2)c(OCC(O)C[C@@H](O)CC([O-])=O)c1C(C)C

InChI Key InChIKey=CJLNTHWSOLNMNY-FIWHBWSRSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007267   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007267(CHEMBL321768 | Sodium; 6-(4'-fluoro-5-hydroxy-3,4,...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007267(CHEMBL321768 | Sodium; 6-(4'-fluoro-5-hydroxy-3,4,...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed