BDBM50007277 CHEMBL177545::Sodium;6-(4'-Fluoro-6-hydroxy-2,4,5-triisopropyl-biphenyl-3-yloxy)-3,5-dihydroxy-hexanoic acid anion;Sodium acetyl

SMILES CC(C)c1c(O)c(-c2ccc(F)cc2)c(C(C)C)c(OC[C@@H](O)C[C@@H](O)CC([O-])=O)c1C(C)C

InChI Key InChIKey=KFESYODZAQTVOQ-UXHICEINSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007277   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007277(CHEMBL177545 | Sodium;6-(4'-Fluoro-6-hydroxy-2,4,5...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007277(CHEMBL177545 | Sodium;6-(4'-Fluoro-6-hydroxy-2,4,5...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed