BDBM50007291 CHEMBL321713::Sodium; 6-[2,4-dichloro-6-(cyclohexyl-difluoro-methyl)-phenoxy]-3,5-dihydroxy-hexanoate

SMILES OC(COc1c(Cl)cc(Cl)cc1C(F)(F)C1CCCCC1)C[C@@H](O)CC([O-])=O

InChI Key InChIKey=HBEFJWHMKNJWPE-KWCCSABGSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007291   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007291(CHEMBL321713 | Sodium; 6-[2,4-dichloro-6-(cyclohex...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of the incorporation of sodium [14C]acetate into cholesterol in HEP G2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50007291(CHEMBL321713 | Sodium; 6-[2,4-dichloro-6-(cyclohex...)
Affinity DataIC50:  85nMAssay Description:In vitro inhibition of HMG-CoA reductase in solubilized rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed