BindingDB logo
myBDB logout

BDBM50007302 CHEMBL101633::Sodium; 6-(2,4-dichloro-6-cyclohexylmethyl-phenoxy)-3,5-dihydroxy-hexanoate

SMILES: OC(COc1c(Cl)cc(Cl)cc1CC1CCCCC1)C[C@@H](O)CC([O-])=O

InChI Key: InChIKey=JFBQKTMQLRVNBD-AAFJCEBUSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007302   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HMG-CoA reductase


(Rattus norvegicus (rat))
BDBM50007302
PNG
(CHEMBL101633 | Sodium; 6-(2,4-dichloro-6-cyclohexy...)
Show SMILES OC(COc1c(Cl)cc(Cl)cc1CC1CCCCC1)C[C@@H](O)CC([O-])=O
Show InChI InChI=1S/C19H26Cl2O5/c20-14-7-13(6-12-4-2-1-3-5-12)19(17(21)8-14)26-11-16(23)9-15(22)10-18(24)25/h7-8,12,15-16,22-23H,1-6,9-11H2,(H,24,25)/p-1/t15-,16?/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 27n/an/an/an/an/an/a



Hoechst AG

Curated by ChEMBL


Assay Description
In vitro inhibition of HMG-CoA reductase in solubilized rat liver.


J Med Chem 34: 2962-83 (1991)


Article DOI: 10.1021/jm00114a004
BindingDB Entry DOI: 10.7270/Q2C829WX
More data for this
Ligand-Target Pair