BDBM50007397 1-(3-Naphthalen-2-yl-propyl)-4-phenyl-piperazine::CHEMBL112037

SMILES C(CN1CCN(CC1)c1ccccc1)Cc1ccc2ccccc2c1

InChI Key InChIKey=ZDMWBBFQNAAKPP-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007397   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(1-(3-Naphthalen-2-yl-propyl)-4-phenyl-piperazine |...)
Affinity DataKi:  4nMAssay Description:Binding affinity of the compound towards sigma receptor in guinea pig brain membranes using [3H]-DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(1-(3-Naphthalen-2-yl-propyl)-4-phenyl-piperazine |...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its affinity towards PCP receptor in rat brain membrane [3H]-MK-801 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(1-(3-Naphthalen-2-yl-propyl)-4-phenyl-piperazine |...)
Affinity DataIC50:  3.00E+3nMAssay Description:Binding affinity of the compound towards Dopamine receptor D1 in rat membranes using [3H]-SCH-23,390 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007397(1-(3-Naphthalen-2-yl-propyl)-4-phenyl-piperazine |...)
Affinity DataIC50:  160nMAssay Description:Compound was tested for its binding affinity towards dopamine receptor D2 by using [3H]-domperidone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed