BDBM50007410 1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine::CHEMBL112125

SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1

InChI Key InChIKey=NAFPAUNPTMADIM-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50007410   

TargetSigma non-opioid intracellular receptor 1(RAT)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50007410(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50007410(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity of the compound towards sigma receptor in guinea pig brain membranes using [3H]-DTG as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50007410(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Affinity DataKi:  391nMAssay Description:Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50007410(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Affinity DataKi:  660nMAssay Description:Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50007410(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat brainstem after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50007410(1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...)
Affinity DataKi:  2.65E+3nMAssay Description:Displacement of [3H]WIN 35428 from dopamine transporter in rat striatum after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed