BDBM50007421 CHEMBL59245::Propionic acid 1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-3-methyl-4-phenyl-piperidin-4-yl ester

SMILES CCC(=O)O[C@]1(CCN(CCCC(=O)c2ccc(F)cc2)CC1C)c1ccccc1

InChI Key InChIKey=REXOMGWVBIKJKZ-BIAFCPFJSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007421   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50007421(CHEMBL59245 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50:  54nMAssay Description:Neuroleptic activity in terms of [3H]-spiroperidol binding to Dopamine receptor D2 in rat striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50007421(CHEMBL59245 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50:  43nMAssay Description:Neuroleptic activity in terms of [3H]-spiroperidol binding to dopamine receptor D2 in rat striatal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50007421(CHEMBL59245 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50:  6.10nMAssay Description:Opioid activity in terms of inhibition of [3H]-dihydromorphine binding to opioid receptor mu in rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Istituto Superiore Di Sanità

Curated by ChEMBL
LigandPNGBDBM50007421(CHEMBL59245 | Propionic acid 1-[4-(4-fluoro-phenyl...)
Affinity DataIC50:  9.5nMAssay Description:Opioid activity in terms of inhibition of [3H]-dihydromorphine binding to Opioid receptor mu 1 in rat brain membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed