BDBM50007474 CHEMBL141432::N-[3-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-propyl]-N-methyl-acetamide(Z isomer)

SMILES CN(CC\C=C1\c2ccc(Cl)cc2CCc2cccnc12)C(C)=O

InChI Key InChIKey=JHOJSIPGICNRRG-SWNXQHNESA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50007474   

TargetHistamine H1 receptor(RAT)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007474(CHEMBL141432 | N-[3-(8-Chloro-5,6-dihydro-benzo[5,...)
Affinity DataKi:  850nMAssay Description:Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor receptor(Homo sapiens (Human))
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50007474(CHEMBL141432 | N-[3-(8-Chloro-5,6-dihydro-benzo[5,...)
Affinity DataIC50: >5.00E+4nMAssay Description:Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed