BDBM50007486 8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethoxy}-8-aza-spiro[4.5]decane-7,9-dione(2.0HCl)::CHEMBL276378

SMILES COc1ccccc1N1CCN(CCON2C(=O)CC3(CCCC3)CC2=O)CC1

InChI Key InChIKey=OFDPQLQCHAJCNC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007486   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007486(8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethoxy}...)
Affinity DataIC50:  370nMAssay Description:Affinity for 5-hydroxytryptamine 1A receptor labeled with [3H]8-OH-DPAT radioligand in hippocampus tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007486(8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethoxy}...)
Affinity DataIC50:  3.20E+3nMAssay Description:Compound was measured for affinity at 5-hydroxytryptamine 2 receptor in rat cortical by [3H]spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50007486(8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethoxy}...)
Affinity DataIC50:  740nMAssay Description:Compound was measured for affinity at dopamine receptor D2 labeled with [3H]spiroperidol radioligand in striatum tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed