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BDBM50007516 (R) N-(1-Benzyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide::CHEMBL176373

SMILES: COc1cccc(C(=O)NC[C@H]2CCCN2Cc2ccccc2)c1OC

InChI Key: InChIKey=JLSSMOBEJBGIRR-QGZVFWFLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007516   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50007516
PNG
((R) N-(1-Benzyl-pyrrolidin-2-ylmethyl)-2,3-dimetho...)
Show SMILES COc1cccc(C(=O)NC[C@H]2CCCN2Cc2ccccc2)c1OC
Show InChI InChI=1S/C21H26N2O3/c1-25-19-12-6-11-18(20(19)26-2)21(24)22-14-17-10-7-13-23(17)15-16-8-4-3-5-9-16/h3-6,8-9,11-12,17H,7,10,13-15H2,1-2H3,(H,22,24)/t17-/m1/s1
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PC sid
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Similars

Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Astra Research Centre AB

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to rat striatal dopamine receptor D2 was determined in vitro


J Med Chem 34: 948-55 (1991)


Article DOI: 10.1021/jm00107a012
BindingDB Entry DOI: 10.7270/Q2GT5NS9
More data for this
Ligand-Target Pair