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BDBM50007527 CHEMBL172536::N-(1-Benzyl-piperidin-4-yl)-3-bromo-2-hydroxy-5,6-dimethoxy-benzamide

SMILES: COc1cc(Br)c(O)c(C(=O)NC2CCN(Cc3ccccc3)CC2)c1OC

InChI Key: InChIKey=HUAOWHVSGILVDD-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007527   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50007527
PNG
(CHEMBL172536 | N-(1-Benzyl-piperidin-4-yl)-3-bromo...)
Show SMILES COc1cc(Br)c(O)c(C(=O)NC2CCN(Cc3ccccc3)CC2)c1OC
Show InChI InChI=1S/C21H25BrN2O4/c1-27-17-12-16(22)19(25)18(20(17)28-2)21(26)23-15-8-10-24(11-9-15)13-14-6-4-3-5-7-14/h3-7,12,15,25H,8-11,13H2,1-2H3,(H,23,26)
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PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.360n/an/an/an/an/an/a



Astra Research Centre AB

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to rat striatal dopamine receptor D2 was determined in vitro


J Med Chem 34: 948-55 (1991)


Article DOI: 10.1021/jm00107a012
BindingDB Entry DOI: 10.7270/Q2GT5NS9
More data for this
Ligand-Target Pair