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BDBM50007528 CHEMBL366766::N-(1-Benzyl-piperidin-4-yl)-3,5-dichloro-2-hydroxy-6-methoxy-benzamide

SMILES: COc1c(Cl)cc(Cl)c(O)c1C(=O)NC1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=KCEKRQOLTANGPT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007528   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50007528
PNG
(CHEMBL366766 | N-(1-Benzyl-piperidin-4-yl)-3,5-dic...)
Show SMILES COc1c(Cl)cc(Cl)c(O)c1C(=O)NC1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C20H22Cl2N2O3/c1-27-19-16(22)11-15(21)18(25)17(19)20(26)23-14-7-9-24(10-8-14)12-13-5-3-2-4-6-13/h2-6,11,14,25H,7-10,12H2,1H3,(H,23,26)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.40n/an/an/an/an/an/a



Astra Research Centre AB

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to rat striatal dopamine receptor D2 was determined in vitro


J Med Chem 34: 948-55 (1991)


Article DOI: 10.1021/jm00107a012
BindingDB Entry DOI: 10.7270/Q2GT5NS9
More data for this
Ligand-Target Pair