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BDBM50007697 4-Methoxy-3-piperazin-1-yl-benzo[d]isothiazole (1.1HCl)::CHEMBL115037

SMILES: COc1cccc2snc(N3CCNCC3)c12

InChI Key: InChIKey=QKFUBSAOOVBJKU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007697   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50007697
PNG
(4-Methoxy-3-piperazin-1-yl-benzo[d]isothiazole (1....)
Show SMILES COc1cccc2snc(N3CCNCC3)c12
Show InChI InChI=1S/C12H15N3OS/c1-16-9-3-2-4-10-11(9)12(14-17-10)15-7-5-13-6-8-15/h2-4,13H,5-8H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 121n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1A receptor of rat hippocampal tissue with [3H]-5-HT


J Med Chem 34: 3316-28 (1991)


Article DOI: 10.1021/jm00115a024
BindingDB Entry DOI: 10.7270/Q29Z93VX
More data for this
Ligand-Target Pair