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BDBM50008058 3-Benzoyloxy-8-benzyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL33039

SMILES: COC(=O)C1C2CC[C@H](CC1OC(=O)c1ccccc1)N2Cc1ccccc1

InChI Key: InChIKey=XYKATAPFAYNVFX-YXOXRFPUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008058   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine Transporter (DAT)


(Rattus norvegicus (rat))
BDBM50008058
PNG
(3-Benzoyloxy-8-benzyl-8-aza-bicyclo[3.2.1]octane-2...)
Show SMILES COC(=O)C1C2CC[C@H](CC1OC(=O)c1ccccc1)N2Cc1ccccc1
Show InChI InChI=1S/C23H25NO4/c1-27-23(26)21-19-13-12-18(24(19)15-16-8-4-2-5-9-16)14-20(21)28-22(25)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3/t18-,19?,20?,21?/m1/s1
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Similars

Article
PubMed
n/an/a 668n/an/an/an/an/an/a



Research Triangle Institute

Curated by ChEMBL


Assay Description
Inhibition of [3H]3-beta-(p-fluorophenyl)tropane-2beta-carboxylic acid methyl ester [3H]7a binding to Dopamine transporter of rat striatal membranes


J Med Chem 35: 141-4 (1992)


Article DOI: 10.1021/jm00079a018
BindingDB Entry DOI: 10.7270/Q29Z95H8
More data for this
Ligand-Target Pair