BDBM50008290 2-{4-[(2-Amino-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid::CHEMBL114987

SMILES Nc1nc2ncc(CN(CC#C)c3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=ZMGMVJDUIACEOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008290   

TargetThymidylate synthase(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50008290(2-{4-[(2-Amino-4-oxo-3,4-dihydro-pyrido[2,3-d]pyri...)
Affinity DataIC50:  90nMAssay Description:The compound was tested for its inhibitory activity against thymidylate synthase(TS) derived from H35F/F cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed