BDBM50008292 2-{4-[(2,4-Diamino-5-methyl-pyrido[2,3-d]pyrimidin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid::CHEMBL112061

SMILES Cc1c(CN(CC#C)c2ccc(cc2)C(=O)NC(CCC(O)=O)C(O)=O)cnc2nc(N)nc(N)c12

InChI Key InChIKey=NXZWILPVWKKBOG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008292   

TargetDihydrofolate reductase(Mus musculus (Mouse))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50008292(2-{4-[(2,4-Diamino-5-methyl-pyrido[2,3-d]pyrimidin...)
Affinity DataKi:  0.00687nMAssay Description:The compound was tested for its inhibitory activity against dihydrofolate reductase(DHFR) derived from L1210 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed