BDBM50008457 CHEMBL140012::{3-[(3-Chloro-phenylthiocarbamoyl)-methyl]-4-oxo-3,4-dihydro-phthalazin-1-yl}-acetic acid

SMILES OC(=O)Cc1nn(CC(=S)Nc2cccc(Cl)c2)c(=O)c2ccccc12

InChI Key InChIKey=GGDBSXWPGBPYLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008457   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50008457(CHEMBL140012 | {3-[(3-Chloro-phenylthiocarbamoyl)-...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibitory activity against aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed