BDBM50008520 2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3,4,5,6-pentahydroxy-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethyl]-3-(2-methyl-propane-2-sulfonyl)-propionamide::CHEMBL357253

SMILES CC(C)(C)S(=O)(=O)CC(Cc1ccccc1)C(=O)NC(Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI Key InChIKey=SEGJVTDZQVOHPV-BGYFKOBFSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50008520   

TargetRenin(Rattus norvegicus)
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3,4,5,6-pentah...)
Affinity DataIC50:  8.00E+3nMAssay Description:Concentration required for 50% inhibition of rat plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3,4,5,6-pentah...)
Affinity DataIC50:  110nMAssay Description:Concentration required for 50% inhibition of dog plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPepsin A-5(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3,4,5,6-pentah...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of pepsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3,4,5,6-pentah...)
Affinity DataIC50:  100nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3,4,5,6-pentah...)
Affinity DataIC50:  11nMAssay Description:Concentration required for 50% inhibition of human kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3,4,5,6-pentah...)
Affinity DataIC50:  4.40nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3,4,5,6-pentah...)
Affinity DataIC50:  4.5nMAssay Description:Concentration required for 50% inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50008520(2-Benzyl-N-[1-(1-cyclohexylmethyl-2,3,4,5,6-pentah...)
Affinity DataIC50: >1.00E+6nMAssay Description:Concentration required for 50% inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed