BDBM50008783 CHEMBL42448::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-(3-fluoro-propyl)-2-hydroxy-5,6-dimethoxy-benzamide
SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(CCCF)cc(OC)c1OC
InChI Key InChIKey=CUVDIPGTXCBTQZ-AWEZNQCLSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50008783
Affinity DataKi: 0.25nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]- spiperone from dopamine receptor D2 of striatal membranes without sodium chlorideMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Compound was evaluated for binding affinity towards dopamine receptor D2 in striatal membranes, using [3H]- spiperone as radioligand in the presence ...More data for this Ligand-Target Pair