BDBM50008851 2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-propionamide; hydrochloride::CHEMBL553114

SMILES CC(C(=O)N(C)[C@H]1CCCC[C@@H]1N1CCCC1)c1cccc2sccc12

InChI Key InChIKey=UMIAZJFHSCKPMM-RFFXKOPCSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50008851   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008851(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  172nMAssay Description:Compound was evaluated for the Opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008851(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  172nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008851(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  176nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008851(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008851(2-Benzo[b]thiophen-4-yl-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataKi:  2.46E+3nMAssay Description:Compound was evaluated for the Opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed