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BDBM50009230 1,3-Diethyl-2-[3-(3-methyl-thiazolidin-2-ylidene)-propenyl]-3H-imidazo[4,5-b]quinoxalin-1-ium; iodide::CHEMBL51135

SMILES: CCn1c(\C=C\C=C2/SCCN2C)[n+](CC)c2nc3ccccc3nc12

InChI Key: InChIKey=BNQDDEHPAOJHLN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009230   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neurokinin 1 receptor


(Rattus norvegicus (rat))
BDBM50009230
PNG
(1,3-Diethyl-2-[3-(3-methyl-thiazolidin-2-ylidene)-...)
Show SMILES CCn1c(\C=C\C=C2/SCCN2C)[n+](CC)c2nc3ccccc3nc12
Show InChI InChI=1S/C20H24N5S/c1-4-24-17(11-8-12-18-23(3)13-14-26-18)25(5-2)20-19(24)21-15-9-6-7-10-16(15)22-20/h6-12H,4-5,13-14H2,1-3H3/q+1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Rochester

Curated by ChEMBL


Assay Description
Binding affinity for tachykinin receptor 1 from rat forebrain tissue, [125I]-BH-SP as radioligand


J Med Chem 34: 1751-3 (1991)


Article DOI: 10.1021/jm00109a034
BindingDB Entry DOI: 10.7270/Q2JQ11MP
More data for this
Ligand-Target Pair