BDBM50009435 10-Difluoromethyl-13-methyl-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-cyclopenta[a]phenanthren-17-one::CHEMBL83835

SMILES CC12CCC3C(CCC4=CCCCC34C(F)F)C1CCC2=O

InChI Key InChIKey=KMFWEHJTLFYKGK-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50009435   

TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009435(10-Difluoromethyl-13-methyl-1,2,3,6,7,8,9,10,11,12...)
Affinity DataKi:  443nMAssay Description:Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedioneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50009435(10-Difluoromethyl-13-methyl-1,2,3,6,7,8,9,10,11,12...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of 1 uM [1-beta-3H]-androstenedione binding to human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed