BDBM50009621 CHEMBL90266::[1-(13-Cyclohexylmethyl-11,12-dihydroxy-2,6-dioxo-1,7diaza-cyclotridec-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCC(=O)NCCC[C@H](O)[C@H](O)[C@H](CC2CCCCC2)NC1=O

InChI Key InChIKey=IXGDPPFLARWURZ-LFGITCQGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009621   

TargetRenin(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009621(CHEMBL90266 | [1-(13-Cyclohexylmethyl-11,12-dihydr...)
Affinity DataIC50:  650nMpH: 7.4Assay Description:The compound was evaluated in vitro for inhibition of human plasma renin at pH 7.4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed