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BDBM50009704 4-Amino-1-(3-chloro-phenyl)-5-methyl-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-6-one::CHEMBL99656

SMILES: Cn1c(N)c2cnn(-c3cccc(Cl)c3)c2nc1=O

InChI Key: InChIKey=CWPMYCGBQCUVQA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009704   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A1


(Rattus norvegicus (rat))
BDBM50009704
PNG
(4-Amino-1-(3-chloro-phenyl)-5-methyl-1,5-dihydro-p...)
Show SMILES Cn1c(N)c2cnn(-c3cccc(Cl)c3)c2nc1=O
Show InChI InChI=1S/C12H10ClN5O/c1-17-10(14)9-6-15-18(11(9)16-12(17)19)8-4-2-3-7(13)5-8/h2-6H,14H2,1H3
PDB

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PC sid
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Similars

Article
PubMed
n/an/a 1.65E+4n/an/an/an/an/an/a



Griffith University

Curated by ChEMBL


Assay Description
Inhibitory concentration against R[3H]-N6-PIA binding to adenosine A1 receptors in rat whole brain membrane


J Med Chem 34: 2892-8 (1991)


Article DOI: 10.1021/jm00113a031
BindingDB Entry DOI: 10.7270/Q2DJ5DMS
More data for this
Ligand-Target Pair