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BDBM50009870 (2-Fluoro-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone::CHEMBL427657

SMILES: Cc1c(C(=O)c2ccccc2F)c2ccccc2n1CCN1CCOCC1

InChI Key: InChIKey=LBVQZINEINQDHE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009870   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009870
PNG
((2-Fluoro-phenyl)-[2-methyl-1-(2-morpholin-4-yl-et...)
Show SMILES Cc1c(C(=O)c2ccccc2F)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C22H23FN2O2/c1-16-21(22(26)17-6-2-4-8-19(17)23)18-7-3-5-9-20(18)25(16)11-10-24-12-14-27-15-13-24/h2-9H,10-15H2,1H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair