BindingDB logo
myBDB logout

BDBM50009871 Benzo[b]thiophen-3-yl-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone::CHEMBL13288

SMILES: Cc1c(C(=O)c2csc3ccccc23)c2ccccc2n1CCN1CCOCC1

InChI Key: InChIKey=JAJHMPAEGHEZIQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009871   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50009871
PNG
(Benzo[b]thiophen-3-yl-[2-methyl-1-(2-morpholin-4-y...)
Show SMILES Cc1c(C(=O)c2csc3ccccc23)c2ccccc2n1CCN1CCOCC1
Show InChI InChI=1S/C24H24N2O2S/c1-17-23(24(27)20-16-29-22-9-5-3-6-18(20)22)19-7-2-4-8-21(19)26(17)11-10-25-12-14-28-15-13-25/h2-9,16H,10-15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair