BDBM50009901 6-(3-Methyl-thioureido)-2-(3-naphthalen-1-yl-2-naphthalen-1-ylmethyl-propionylamino)-hexanoic acid {4-[2-(2-amino-ethyl)-morpholin-4-yl]-2-hydroxy-1-isobutyl-4-oxo-butyl}-amide::CHEMBL281134

SMILES CNC(=S)NCCCCC(NC(=O)C(Cc1cccc2ccccc12)Cc1cccc2ccccc12)C(=O)NC(CC(C)C)[C@@H](O)CC(=O)N1CCOC(CCN)C1

InChI Key InChIKey=QJWWZBWMLPVXMI-WHIWUVKUSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50009901   

TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50009901(6-(3-Methyl-thioureido)-2-(3-naphthalen-1-yl-2-nap...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50009901(6-(3-Methyl-thioureido)-2-(3-naphthalen-1-yl-2-nap...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibitory activity against bovine cathepsin D was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50009901(6-(3-Methyl-thioureido)-2-(3-naphthalen-1-yl-2-nap...)
Affinity DataIC50:  125nMAssay Description:Inhibitory activity against monkey plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed