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BDBM50009993 CHEMBL67410::[4-(3-Phenyl-propionylamino)-benzoylamino]-acetic acid

SMILES: OC(=O)CNC(=O)c1ccc(NC(=O)CCc2ccccc2)cc1

InChI Key: InChIKey=OBKUKGZZSPNFIH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50009993   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase


(Rattus norvegicus)
BDBM50009993
PNG
(CHEMBL67410 | [4-(3-Phenyl-propionylamino)-benzoyl...)
Show SMILES OC(=O)CNC(=O)c1ccc(NC(=O)CCc2ccccc2)cc1
Show InChI InChI=1S/C18H18N2O4/c21-16(11-6-13-4-2-1-3-5-13)20-15-9-7-14(8-10-15)18(24)19-12-17(22)23/h1-5,7-10H,6,11-12H2,(H,19,24)(H,20,21)(H,22,23)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.50E+4n/an/an/an/an/an/a



Auburn University

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase in rat lens


J Med Chem 34: 2120-6 (1991)


Article DOI: 10.1021/jm00111a030
BindingDB Entry DOI: 10.7270/Q2N29VX2
More data for this
Ligand-Target Pair