BDBM50010041 CHEMBL84087::{1-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]isothiazol-2-yl)-propyl]-piperidin-4-yl}-(4-fluoro-phenyl)-methanone

SMILES Fc1ccc(cc1)C(=O)C1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1

InChI Key InChIKey=YGCLJBSIKQLHLJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010041   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
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Curated by ChEMBL
LigandPNGBDBM50010041(CHEMBL84087 | {1-[3-(1,1-Dioxo-1H-1lambda*6*-napht...)
Affinity DataIC50:  41nMAssay Description:The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
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Curated by ChEMBL
LigandPNGBDBM50010041(CHEMBL84087 | {1-[3-(1,1-Dioxo-1H-1lambda*6*-napht...)
Affinity DataIC50:  7.90nMAssay Description:The concentration required to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat brain membranes was measured (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
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Curated by ChEMBL
LigandPNGBDBM50010041(CHEMBL84087 | {1-[3-(1,1-Dioxo-1H-1lambda*6*-napht...)
Affinity DataIC50:  0.100nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed