BDBM50010289 (R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(RS)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL109684::N-0434

SMILES CCCN(CCc1ccccc1)C1CCc2c(O)cccc2C1

InChI Key InChIKey=DEYFWGXTPWNADC-UHFFFAOYSA-N

Data  11 KI  6 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50010289   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  0.260nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]N-0437 binding on Dopamine receptor D2L of CHO K-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Neuroscience Research Centre

Curated by PDSP Ki Database
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D3 expressed on CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  5.90nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H] spiperone from human D2 dopamine receptor expressed in monkey caudate-putamen membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  13nMAssay Description:Binding affinity against dopamine receptor D2 by using [3H]spiperone as radioligand in caudate-putamen of monkeyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  19nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D2L of CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  20nMAssay Description:Affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  54nMAssay Description:Binding affinity was evaluated by calculating competition for [3H]spiperone binding on Dopamine receptor D4.2 of CHO K-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  804nMAssay Description:Binding affinity against dopamine receptor D1 by using [3H]-SCH- 23390 as radioligand in caudate-putamen of monkeyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Research Biochemicals

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKi:  1.20E+3nMAssay Description:Affinity towards Dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  12nMAssay Description:In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  34nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  90nMAssay Description:In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Texas

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  10nMAssay Description:In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  4.30nMAssay Description:Binding affinity to SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Groningen

Curated by ChEMBL
LigandPNGBDBM50010289((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...)
Affinity DataKd:  4.30nMAssay Description:Binding affinity to SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed