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BDBM50010719 3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,5-dihydroxy-6-methoxy-benzamide::CHEMBL77492

SMILES: CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(O)c1OC

InChI Key: InChIKey=MRDDDUTZQYNACV-VIFPVBQESA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010719   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50010719
PNG
(3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,5-dihy...)
Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(O)c1OC
Show InChI InChI=1S/C15H21BrN2O4/c1-3-18-6-4-5-9(18)8-17-15(21)12-13(20)10(16)7-11(19)14(12)22-2/h7,9,19-20H,3-6,8H2,1-2H3,(H,17,21)/t9-/m0/s1
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90n/an/an/an/an/an/a



Astra Research Centre AB

Curated by ChEMBL


Assay Description
The affinity for the Dopamine receptor D2 was assessed by the inhibition of [3H]-spiperone binding in rat striatal membranes in vitro.


J Med Chem 33: 2305-9 (1990)


Article DOI: 10.1021/jm00170a040
BindingDB Entry DOI: 10.7270/Q29P30MH
More data for this
Ligand-Target Pair