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BDBM50010880 1-(2-Dimethylamino-1-p-tolyl-ethyl)-cyclohexanol (HCl)::CHEMBL99670

SMILES: CN(C)CC(c1ccc(C)cc1)C1(O)CCCCC1

InChI Key: InChIKey=OPDPMFSQSBDMAI-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010880   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50010880
PNG
(1-(2-Dimethylamino-1-p-tolyl-ethyl)-cyclohexanol (...)
Show SMILES CN(C)CC(c1ccc(C)cc1)C1(O)CCCCC1
Show InChI InChI=1S/C17H27NO/c1-14-7-9-15(10-8-14)16(13-18(2)3)17(19)11-5-4-6-12-17/h7-10,16,19H,4-6,11-13H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.54E+3n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomes


J Med Chem 33: 2899-905 (1990)


Article DOI: 10.1021/jm00172a035
BindingDB Entry DOI: 10.7270/Q20C4WCM
More data for this
Ligand-Target Pair
Alpha-1A adrenergic receptor


(Rattus norvegicus (Rat))
BDBM50010880
PNG
(1-(2-Dimethylamino-1-p-tolyl-ethyl)-cyclohexanol (...)
Show SMILES CN(C)CC(c1ccc(C)cc1)C1(O)CCCCC1
Show InChI InChI=1S/C17H27NO/c1-14-7-9-15(10-8-14)16(13-18(2)3)17(19)11-5-4-6-12-17/h7-10,16,19H,4-6,11-13H2,1-3H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 205n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Inhibition of binding of [3H]imipramine to imipramine receptor in rat brain


J Med Chem 33: 2899-905 (1990)


Article DOI: 10.1021/jm00172a035
BindingDB Entry DOI: 10.7270/Q20C4WCM
More data for this
Ligand-Target Pair
Norepinephrine Monoamine transporters


(Rattus norvegicus)
BDBM50010880
PNG
(1-(2-Dimethylamino-1-p-tolyl-ethyl)-cyclohexanol (...)
Show SMILES CN(C)CC(c1ccc(C)cc1)C1(O)CCCCC1
Show InChI InChI=1S/C17H27NO/c1-14-7-9-15(10-8-14)16(13-18(2)3)17(19)11-5-4-6-12-17/h7-10,16,19H,4-6,11-13H2,1-3H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 530n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomes


J Med Chem 33: 2899-905 (1990)


Article DOI: 10.1021/jm00172a035
BindingDB Entry DOI: 10.7270/Q20C4WCM
More data for this
Ligand-Target Pair