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BDBM50010881 1-[2-Dimethylamino-1-(4-trifluoromethyl-phenyl)-ethyl]-cyclopentanol (HCl)::CHEMBL100773

SMILES: CN(C)CC(c1ccc(cc1)C(F)(F)F)C1(O)CCCC1

InChI Key: InChIKey=FTIPYTODMKUPGF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50010881   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Norepinephrine Monoamine transporters


(Rattus norvegicus)
BDBM50010881
PNG
(1-[2-Dimethylamino-1-(4-trifluoromethyl-phenyl)-et...)
Show SMILES CN(C)CC(c1ccc(cc1)C(F)(F)F)C1(O)CCCC1
Show InChI InChI=1S/C16H22F3NO/c1-20(2)11-14(15(21)9-3-4-10-15)12-5-7-13(8-6-12)16(17,18)19/h5-8,14,21H,3-4,9-11H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.04E+4n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomes


J Med Chem 33: 2899-905 (1990)


Article DOI: 10.1021/jm00172a035
BindingDB Entry DOI: 10.7270/Q20C4WCM
More data for this
Ligand-Target Pair
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50010881
PNG
(1-[2-Dimethylamino-1-(4-trifluoromethyl-phenyl)-et...)
Show SMILES CN(C)CC(c1ccc(cc1)C(F)(F)F)C1(O)CCCC1
Show InChI InChI=1S/C16H22F3NO/c1-20(2)11-14(15(21)9-3-4-10-15)12-5-7-13(8-6-12)16(17,18)19/h5-8,14,21H,3-4,9-11H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 490n/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomes


J Med Chem 33: 2899-905 (1990)


Article DOI: 10.1021/jm00172a035
BindingDB Entry DOI: 10.7270/Q20C4WCM
More data for this
Ligand-Target Pair