BDBM50010933 2-{4-[(4-Amino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-pentanedioic acid::CHEMBL74422

SMILES CN(Cc1cnc2ncnc(N)c2n1)c1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O

InChI Key InChIKey=UVTFJYBNKBVDDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50010933   

TargetDihydrofolate reductase(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50010933(2-{4-[(4-Amino-pteridin-6-ylmethyl)-methyl-amino]-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Compound was evaluated for Dihydrofolate Reductase (DHFR) inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed