BDBM50010958 2,3,5-Trimethyl-6-(1-pyridin-3-yl-heptyl)-[1,4]benzoquinone::CHEMBL328487

SMILES CCCCCC=C(c1cccnc1)c1c(C)c(O)c(C)c(C)c1O

InChI Key InChIKey=SQTZKYZSLRJSPG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50010958   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010958(2,3,5-Trimethyl-6-(1-pyridin-3-yl-heptyl)-[1,4]ben...)
Affinity DataIC50:  600nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010958(2,3,5-Trimethyl-6-(1-pyridin-3-yl-heptyl)-[1,4]ben...)
Affinity DataIC50:  73nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50010958(2,3,5-Trimethyl-6-(1-pyridin-3-yl-heptyl)-[1,4]ben...)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed