BDBM50011016 4-(4-Cyano-phenyl)-5-(4-fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL331411

SMILES CCOC(=O)c1c(C(C)C)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c(c1-c1ccc(cc1)C#N)-c1ccc(F)cc1

InChI Key InChIKey=IYDDXEIYERNMIL-DNQXCXABSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011016   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50011016(4-(4-Cyano-phenyl)-5-(4-fluoro-phenyl)-1-[2-(4-hyd...)
Affinity DataIC50:  280nMAssay Description:Inhibition of HMG-CoA reductase activity in partially purified rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed