BDBM50011300 CHEMBL2398482::US9133197, 2
SMILES CC(O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1
InChI Key InChIKey=HMSFWLUZEDMXMM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50011300
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
US Patent
Sigma-Tau Industrie Farmaceutiche Riunite
US Patent
Affinity DataKi: 8nMpH: 7.4Assay Description:The protein concentration of membrane suspension was determined using the Bradford method (Pierce, Rockford, Ill., USA) with bovine albumin as standa...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
US Patent
Sigma-Tau Industrie Farmaceutiche Riunite
US Patent
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant adenosine receptor A2aMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
US Patent
Sigma-Tau Industrie Farmaceutiche Riunite
US Patent
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 1 hr by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Inhibition of human recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 27nM ΔG°: -10.3kcal/molepH: 7.4 T: 2°CAssay Description:Competition binding experiments have been performed incubating membranes from CHO-K1 cells stably transfected with the human adenosine A1 receptor (c...More data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO-K1 cells after 60 minsMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
Sigma-Tau Industrie Farmaceutiche Riunite
US Patent
Sigma-Tau Industrie Farmaceutiche Riunite
US Patent
Affinity DataIC50: 450nMAssay Description:Antagonist activity at human adenosine A2A receptor expressed in HEK293 cells assessed as inhibition of NECA-induced cAMP accumulation incubated for ...More data for this Ligand-Target Pair