BDBM50011342 2-Amino-5-[2-(1-{[1-(1-cyclohexylmethyl-2-hydroxy-5-methyl-4-{2-methyl-1-[(1-oxy-pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexylcarbamoyl)-2-(3H-imidazol-4-yl)-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-pyrrolidin-1-yl]-5-oxo-pentanoicacid::CHEMBL3143481

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)CC[C@H](N)C(O)=O)C(C)C)C(=O)NCc1cccc[n+]1[O-]

InChI Key InChIKey=QQYKRBILVSWRSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011342   

TargetRenin(Homo sapiens (Human))
Upjohn

Curated by ChEMBL
LigandPNGBDBM50011342(2-Amino-5-[2-(1-{[1-(1-cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of human plasma renin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed