BDBM50011851 2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo[3.2.1]oct-3-yl ester::2,2-Diphenyl-propionic acid 6-methyl-6-aza-bicyclo[3.2.1]oct-3-yl ester (azaprophen)::CHEMBL287868
SMILES CN1CC2CC1CC(C2)OC(=O)C(C)(c1ccccc1)c1ccccc1
InChI Key InChIKey=WOMCGBFNBSIIEA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 25 hits for monomerid = 50011851
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.More data for this Ligand-Target Pair
Affinity DataKi: 0.0383nMAssay Description:The compound was tested for binding activity against muscarinic acetylcholine receptor M1, using [3H]QNB as the radioligand.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0540nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileumMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.0880nMAssay Description:Inhibition of [3H]QNB binding to CHO cells bearing transfected muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
Affinity DataKi: 0.0986nMAssay Description:The compound was tested for binding activity against muscarinic acetylcholine receptor M3, using [3H]-QNB as the radioligand.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.118nMAssay Description:Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.196nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat heart.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Inhibit the binding of [N-mnethyl-3H]-scopolamine [3H]-NMS) to Muscarinic acetylcholine receptor of human IRM-30 neuroblastoma cellsMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 0.472nMAssay Description:Inhibition of [3H]QNB binding to CHO cells bearing transfected muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 6.36nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 6.40nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat brain.More data for this Ligand-Target Pair
Affinity DataKi: 7.89nMAssay Description:Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Binding activity against rat muscarinic acetylcholine receptor M1 using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 9.60nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataKi: 10.7nMAssay Description:Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding activity against rat muscarinic acetylcholine receptor M3 using [3H]QNB as the radioligandMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of [3H]pirenzepine binding against muscarinic acetylcholine receptor in rat brain.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in rat heart.More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 14.5nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileumMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of [3H]QNB binding against muscarinic acetylcholine receptor in guinea pig ileumMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKd: 3.60nMAssay Description:Inhibition of methacholine induced phasic contraction of guinea pig ileumMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Homo sapiens (Human))
Research Triangle Institute
Curated by ChEMBL
Research Triangle Institute
Curated by ChEMBL
Affinity DataKd: 0.0347nMAssay Description:Inhibition of methacholine induced phasic contraction of guinea pig ileumMore data for this Ligand-Target Pair