BDBM50012050 2-({5-[(2-Fluoro-ethyl)-(2-fluoromethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-thiophene-2-carbonyl}-amino)-pentanedioic acid::CHEMBL539936

SMILES OC(=O)CC[C@@H](NC(=O)c1ccc(s1)N(CCF)Cc1ccc2nc(CF)[nH]c(=O)c2c1)C(O)=O

InChI Key InChIKey=GOLAKUGCJQDMTM-OAHLLOKOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012050   

TargetThymidylate synthase(Mus musculus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50012050(2-({5-[(2-Fluoro-ethyl)-(2-fluoromethyl-4-oxo-3,4-...)
Affinity DataIC50:  1.07E+3nMAssay Description:In vitro inhibition of partially purified L1210 thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed