BindingDB logo
myBDB logout

BDBM50012448 2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7,8-dimethoxy-3-methyl-chromen-4-one::CHEMBL68562

SMILES: COc1cc(O)c2c(oc(c(C)c2=O)-c2ccc(O)c(O)c2)c1OC

InChI Key: InChIKey=NCTBPFJJDLNYLR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50012448   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arachidonate 5-lipoxygenase


(Homo sapiens (Human))
BDBM50012448
PNG
(2-(3,4-Dihydroxy-phenyl)-5-hydroxy-7,8-dimethoxy-3...)
Show SMILES COc1cc(O)c2c(oc(c(C)c2=O)-c2ccc(O)c(O)c2)c1OC
Show InChI InChI=1S/C18H16O7/c1-8-15(22)14-12(21)7-13(23-2)17(24-3)18(14)25-16(8)9-4-5-10(19)11(20)6-9/h4-7,19-21H,1-3H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 300n/an/an/an/an/an/a



University of Tokushima

Curated by ChEMBL


Assay Description
Inhibition of arachidonate 5-lipoxygenase purified from porcine leukocytes.


J Med Chem 34: 2169-76 (1991)


Article DOI: 10.1021/jm00111a037
BindingDB Entry DOI: 10.7270/Q2J10250
More data for this
Ligand-Target Pair