BDBM50012764 (+/-)-6'-chloro-2'-methyl-(2'R,4'S)-spiro[1H,2H-imidazole-4,4'-(3',4'-dihydro-2'H-pyrano[2,3-b]pyridine)]-2,5-dione::CHEMBL56453

SMILES C[C@@H]1C[C@]2(NC(=O)NC2=O)c2cc(Cl)cnc2O1

InChI Key InChIKey=WFPFAWQUEPGPQT-GCXOYZPQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50012764   

TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012764((+/-)-6'-chloro-2'-methyl-(2'R,4'S)-spiro[1H,2H-im...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibitory activity against Aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50012764((+/-)-6'-chloro-2'-methyl-(2'R,4'S)-spiro[1H,2H-im...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibitory activity against Aldose reductase isolated from human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed