BDBM50012798 (E)-2,6-dimethyl-4-styrylphenol::2,6-Dimethyl-4-styryl-phenol::2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol::2,6-dimethyl-4-styrylphenol::CHEMBL55960

SMILES Cc1cc(\C=C\c2ccccc2)cc(C)c1O

InChI Key InChIKey=PAHKYLUYTGBFNW-CMDGGOBGSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012798   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012798((E)-2,6-dimethyl-4-styrylphenol | 2,6-Dimethyl-4-s...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012798((E)-2,6-dimethyl-4-styrylphenol | 2,6-Dimethyl-4-s...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012798((E)-2,6-dimethyl-4-styrylphenol | 2,6-Dimethyl-4-s...)
Affinity DataIC50:  3.08E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair